BPC-157, TB-500 and GHK-Cu are three research peptides supplied together in a single lyophilised blend. AminoOptimization Group supplies this combination as a 70 mg research powder, tested to 99% purity by HPLC, with a Certificate of Analysis available for the lot supplied. This material is offered strictly for laboratory research use. It is not a drug, and it is not for human or veterinary use.
What is BPC-157 / TB-500 / GHK-Cu?
This product combines three structurally unrelated peptides, each the subject of a distinct line of published research, into a single research reagent. Each retains its own chemical identity within the blend.
BPC-157
BPC-157 (Body Protection Compound-157) is a synthetic pentadecapeptide — a chain of 15 amino acids — corresponding to a stable partial sequence identified within a larger protein detected in human gastric juice. It is reported in the literature as unusually resistant to degradation in acidic and enzymatic conditions relative to many other peptide fragments, a property that recurs as a point of interest across published study designs.
TB-500
TB-500 is the name most commonly used in the research-peptide trade for synthetic Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid protein first isolated from thymic tissue. Some suppliers use “TB-500” to denote the full-length protein, and others use it for a shorter synthetic fragment spanning its actin-binding domain; researchers running sequence-dependent assays should confirm which form a given lot represents.
GHK-Cu
GHK-Cu is the copper(II) complex of the tripeptide glycyl-L-histidyl-L-lysine (GHK), a naturally occurring copper-binding peptide first identified in human plasma. The copper ion is coordinated through the peptide’s histidine and terminal amino groups, and much of the published interest in GHK-Cu concerns this coordination chemistry — how peptide-bound copper behaves differently from free copper ions in solution.
Specifications
- Compound: BPC-157 / TB-500 / GHK-Cu (peptide blend)
- CAS number: N/A (blend)
- Molecular formula: N/A (blend)
- Molecular weight: N/A (blend)
- Purity: 99% by HPLC
- Presentation: Lyophilised powder blend, sealed vial
- Available sizes: 70 mg
- Physical form: White to off-white powder
- Classification: Research peptide blend — not for human or veterinary use
Because this product combines three distinct peptides rather than a single defined substance, no single CAS number, molecular formula or molecular weight applies to it as a whole. Each component has its own chemical identity; the combination itself does not.
Research context
Published research on BPC-157 concentrates heavily on gastrointestinal and connective-tissue model systems. Studies in rodents have examined how the peptide’s presence during experimentally induced gastric, intestinal or tendon injury correlates with markers of tissue integrity, and a separate body of work looks at its interaction with angiogenesis-related signalling, including reported effects on VEGFR2 expression and nitric-oxide pathways in cell and animal models.
Literature on Tβ4 / TB-500 centres on its role as an actin-monomer-binding protein. Because actin polymerisation underlies cell migration, published study designs frequently use Tβ4 to probe cytoskeletal dynamics in cell-culture assays and in animal models of experimentally induced tissue damage.
GHK-Cu research sits mainly in dermatology and wound-model literature, where it is examined for its influence on matrix metalloproteinase expression and collagen-related signalling in fibroblast cultures and animal skin models, alongside separate work on its copper-chelating chemistry.
Some published protocols examine peptides with these three mechanisms — extracellular matrix remodelling, actin dynamics and copper-dependent signalling — in combination, since they act through distinct pathways; researchers use such designs to study pathway interaction rather than any single mechanism in isolation. None of this literature establishes safety or efficacy for use in humans. It is provided as research context only.
Reconstitution
Lyophilised peptide blends require reconstitution with a suitable sterile diluent before use in solution. Bacteriostatic water is the diluent most commonly specified for multi-use laboratory preparations; sterile water is typical for single-use work.
Direct the diluent stream against the inner wall of the vial rather than onto the powder itself, and allow the material to dissolve without agitation. Peptides are susceptible to shear stress — do not shake the vial. Swirl gently if needed.
Because this vial contains three peptides rather than one, treat the 70 mg figure as total peptide content rather than assume an equal three-way split unless your protocol specifies otherwise. Our peptide reconstitution calculator computes the resulting concentration for a given vial size and diluent volume.
Storage and stability
Before reconstitution: store the sealed vial in a freezer at -20 °C, protected from light. Lyophilised peptide is comparatively stable in this state, and brief temperature excursions during shipping are normal.
After reconstitution: refrigerate at 2–8 °C and protect from light. Reconstituted peptide in solution is materially less stable than the dry powder. Avoid repeated freeze-thaw cycles — aliquot instead if repeated sampling is required.
Inspect solutions before use. Cloudiness, visible particulate, or discolouration indicate the material should not be relied upon for quantitative work.
Certificate of Analysis
Each lot of this blend is tested by high-performance liquid chromatography, and the purity figure shown above refers to the combined peptide content of the specific lot supplied — not to a generic specification. A Certificate of Analysis is available on request, and we will provide lot-specific documentation before purchase if your protocol requires it.
Purity by HPLC describes the proportion of target peptide relative to detectable related substances. It is a statement about the material as manufactured and tested. It is expressly not a representation that the material is suitable for any use in humans or animals.
Handling and safety
Handle in accordance with good laboratory practice. Use appropriate personal protective equipment, work in a suitable containment environment, and dispose of material and consumables according to your institution’s requirements and applicable local regulation.
Frequently asked questions
What is in the BPC-157 / TB-500 / GHK-Cu blend?
This product combines three peptides in a single vial: BPC-157, TB-500 (a Thymosin Beta-4–related peptide) and GHK-Cu, a copper-bound tripeptide. Each is manufactured and tested independently before being combined into one lyophilised preparation.
Why isn’t there a CAS number listed for this product?
A CAS number identifies a single defined substance. Because this product is a combination of three distinct peptides rather than one substance, no single CAS number, molecular formula or molecular weight applies to the blend as a whole.
Is BPC-157 / TB-500 / GHK-Cu approved in Canada?
No. This blend, and none of the individual peptides within it, has been evaluated or authorised by Health Canada, the FDA, or any comparable regulatory authority. It carries no DIN or NPN, and it is supplied for laboratory research only.
How much diluent should be used for a 70 mg vial?
That depends on the working concentration your protocol requires. Use the reconstitution calculator to work out the resulting concentration for a 70 mg vial.
Do you provide a Certificate of Analysis for blend products?
Yes — lot-specific, available on request, including before purchase.
Research use only
This product is supplied solely for laboratory and scientific research. It is not a drug, food, cosmetic, or medical device, and it must not be administered to humans or animals. Nothing on this page is medical advice or a therapeutic claim. Full terms are set out in our Research Use Only Disclaimer.
Reviews
There are no reviews yet.