Quality Control & Certificates of Analysis

Quality Control & Certificates of Analysis

Every compound we supply carries published analytical data: a CAS number, a molecular formula, a molecular weight, and a purity figure determined by HPLC. Those numbers are printed on the product page before you buy, and the underlying Certificate of Analysis is tied to the specific lot you receive — not to a generic specification sheet.

This page explains what we test, what the certificate actually proves, and how to verify the lot in your hand.

Look up your COA

Enter the lot number printed on your vial label to retrieve the Certificate of Analysis for that specific lot.

Lot numbers are an exact alphanumeric match. If your lot does not return a result, contact us with the number and the product and we will send the certificate directly.

What a Certificate of Analysis actually proves

A Certificate of Analysis is a record of what an analytical laboratory measured in a specific batch of material. It is not a safety assessment, not an approval, and not a statement that the material is fit for any particular use.

A COA tells you three things worth knowing:

  • Identity — that the material is the compound it claims to be, confirmed by mass spectrometry against the expected molecular weight.
  • Purity — what proportion of the sample is the target peptide, versus related substances, residual solvents, and synthesis by-products.
  • Traceability — that the result belongs to an identifiable lot, so the vial in your hand can be matched to the data.

That last point is the one most often missing in this market. A purity figure with no lot reference is an advertising claim. A purity figure tied to a lot number you can look up is a record.

HPLC analysis

High-performance liquid chromatography separates the components of a sample by pushing it through a column under pressure. Different compounds travel at different rates, so they emerge at different times and register as separate peaks on a chromatogram.

Purity is calculated from the area under those peaks: the target peptide’s peak area as a percentage of total peak area. When we state ≥99% purity by HPLC, that is what the figure refers to.

Two things are worth understanding about that number. First, it is a relative measure — it describes composition, not concentration, and says nothing about how much peptide is in the vial by mass. Second, HPLC detects what it is configured to detect; a purity figure is only as meaningful as the method behind it, which is why the chromatogram and method parameters appear on the certificate rather than just the final percentage.

What is on our certificates

  • Product name and lot number
  • CAS number, molecular formula and molecular weight
  • Purity result, expressed as a percentage by HPLC
  • The chromatogram the result was read from
  • Mass spectrometry identity confirmation
  • Appearance and physical description
  • Date of analysis

What we publish before you buy

Every product page on this site states the CAS number, molecular formula, molecular weight and purity specification for that compound. You do not need to place an order or create an account to see them, and you can request the lot-specific certificate before purchasing rather than after.

We would rather answer an analytical question before a sale than defend a claim after one.

Storage, stability and why handling matters

A certificate describes material as it was tested. What happens afterwards is a function of handling. Lyophilised peptide stored at -20 °C and protected from light is comparatively stable; the same material reconstituted, left at room temperature, and freeze-thawed repeatedly is not.

If your work depends on concentration accuracy, validate stability under your own storage conditions rather than assuming the certificate figure persists indefinitely. Our reconstitution calculator covers the arithmetic of preparing a solution; it does not model degradation.

Quality control questions

Is the purity figure specific to my lot?

Yes. The certificate is generated from analysis of a specific batch and carries that lot number. The specification shown on a product page is what that compound is manufactured to; the certificate is what a given lot measured.

Can I get a COA before I order?

Yes. Contact us with the product and we will provide the current lot’s certificate. If your protocol requires particular analytical parameters, tell us before ordering so we can confirm whether the documentation meets them.

Does a COA mean the product is safe or approved?

No. A Certificate of Analysis is an analytical record, not a regulatory authorisation. Nothing we supply has been evaluated or authorised by Health Canada, the FDA, or any comparable body, and nothing we supply is for human or veterinary use. See our Research Use Only Disclaimer.

What does ≥99% purity mean in practice?

It means that at least 99% of the total peak area on the chromatogram is attributable to the target peptide. It is a measure of relative composition, not of mass, concentration, or biological activity.

What if my lot number returns no result?

Contact us with the lot number and product name. Lookup requires an exact alphanumeric match, and a missing result usually means a transcription difference rather than a missing certificate.

Research use only

All products supplied by AminoOptimization Group are for laboratory and scientific research use only. They are not drugs, foods, cosmetics, or medical devices, and must not be administered to humans or animals. Analytical documentation describes the material as manufactured and tested; it is expressly not a representation of fitness for any use in humans or animals. Full terms are set out in our Research Use Only Disclaimer.

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